Peptide Blend Weight Loss

Cagrilintide + Semaglutide 10mg Blend

Components: Cagrilintide + Semaglutide

A dual GLP-1/amylin analogue weight loss blend combining Cagrilintide (5mg) and Semaglutide (5mg) in a 10mg vial. Mirrors the CagriSema mechanism studied in clinical trials for obesity treatment.

Vial size10mg
BAC water3mL
Concentration3.33mg/mL
Components2
Vials needed1 (pre-mixed)
Pre-mixed Blend
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Formulation

Blend Composition

This is a single pre-mixed vial — one reconstitution for all components.

Cagrilintide 5mg 50%
Semaglutide 5mg 50%
Why It Works

Synergy Explanation

Semaglutide activates GLP-1 receptors to suppress appetite, slow gastric emptying, and improve glycemic control. Cagrilintide is a long-acting amylin analogue that provides complementary satiety signaling through the amylin receptor. The combination (CagriSema) addresses two independent satiety axes, producing greater weight loss than either agent alone in clinical research.

Step by Step

Reconstitution Guide

Vial Size10mg
BAC Water3mL
Concentration3.33mg/mL

  1. Allow the vial to reach room temperature for 5 minutes before handling.

  2. Draw 3.0 mL of bacteriostatic water into a sterile syringe.

  3. Sterilize the vial stopper with an alcohol swab and allow to dry.

  4. Inject the BAC water slowly down the inside wall of the vial.

  5. Gently swirl or roll until fully dissolved. Do not shake.

  6. Label with reconstitution date and store refrigerated at 2u20138 u00b0C (35.6u201346.4 u00b0F).

Always use bacteriostatic water — not sterile water — to extend shelf life of your reconstituted blend.

Reference Table

Dosage Protocols

ProtocolDoseFrequencyDurationRouteNotes
Weekly Titration Protocol 250 mcg each (Cagrilintide + Semaglutide) starting dose, titrating to 2400 mcg each Once weekly 16u201320 weeks SubQ Begin at 250 mcg each per week. Increase gradually every 4 weeks as tolerated. Maximum studied dose is 2400 mcg each per week. GI side effects are most pronounced in the first 4u20138 weeks.
Handling

Storage Instructions

Lyophilized (Dry)

Store at ≤−15 °C (5 °F). For long-term storage, ≤−50 °C (−58 °F) preferred.

Reconstituted

Refrigerate at 2–8 °C (35.6–46.4 °F). Use within 3–4 weeks. Do not freeze after reconstitution.

Keep the reconstituted vial refrigerated at all times. Protect from light.

What You Need

Supplies Needed

  • Bacteriostatic water (BAC water) 10 mL vial
  • Insulin syringes (U-100) 0.5 mL, 29u201331 gauge
  • Alcohol swabs For stopper and injection site sterilization
Safety

Potential Side Effects

Nausea, vomiting, and GI discomfort (especially during titration). Decreased appetite (expected mechanism). Injection site reactions. Both agents are long-acting; side effects can persist for days after administration.

Frequently Asked

Questions about Cagrilintide + Semaglutide 10mg Blend